ORAL PATHOLOGY : Infectious diseases with manifestations in oral cavity

We are surrounded and inhabited by an enormous number of microorganisms.

• Whether the organisms cause disease depends on the microorganism and the body’s defenses.

• Traditionally, the microorganisms are divided according to whether they are disease causing (pathogenic) or non–disease causing (nonpathogenic).

• The oral cavity may be the primary site of involvement of an infectious disease, or a systemic infection may have oral manifestations.

• There are different routes of infection:

Read also: ORAL MEDICINE : A guide to common oral lesions

- Transferred through the air on dust particles or water droplets
- Some may require intimate and direct contact.
- Some may be transferred by hands or objects.

Microorganisms invading oral tissue can cause local infection, systemic infection, or both.

• Microorganisms in the bloodstream can cause lesions in the oral cavity.
• Microorganisms causing infection in the lungs can be transferred to oral tissue and be present in saliva.

• Oral flora may be affected by changes in salivary flow, administration of antibiotics, and changes in the immune system.

• Opportunistic infection:
When an organism that usually is nonpathogenic causes disease


Assoc. Prof. G. Tomov, PhD


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